![]() ![]() Other risk factors include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem. Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, gum infection, or slow healing after dental work. Prolia may cause bone loss (osteonecrosis) in the jaw. ![]() Kidney disease (or if you are on dialysis) Ī weak immune system (caused by disease or by using certain medicines) Ī history of hypoparathyroidism (decreased functioning of the parathyroid glands) Ī history of surgery to remove part of your intestine Īny condition that makes it hard for your body to absorb nutrients from food (malabsorption) or To make sure Prolia is safe for you, tell your doctor if you have: While you are using Prolia, you should not use Xgeva, another brand of denosumab. You should not use Prolia if you are allergic to denosumab, or if you have low levels of calcium in your blood (hypocalcemia). You may need to stop using the medicine for a short time. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using Prolia. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Symptoms may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. Some people using Prolia have developed bone loss in the jaw, also called osteonecrosis of the jaw. Call your doctor right away if you have signs of infection such as: severe skin irritation swelling or redness anywhere on your body pain or burning when you urinate severe stomach pain ear pain, trouble hearing cough, feeling short of breath purple or red spots under your skin or fever, chills, night sweats, flu symptoms, or weight loss. Serious infections may occur during treatment with Prolia. Do not use if you are pregnant.īefore you receive Prolia, tell your doctor if you have kidney disease (or if you are on dialysis), a weak immune system, a history of hypoparathyroidism or thyroid surgery, a history of intestinal surgery, a condition that makes it hard for your body to absorb nutrients from food, or if you are allergic to latex. Prolia can harm an unborn baby or cause birth defects. ![]() You should not receive Prolia if you have low levels of calcium in your blood (hypocalcemia). Xgeva is another brand of denosumab used to prevent bone fractures and other skeletal conditions in people with tumors that have spread to the bone. ![]() This medication guide provides information about the Prolia brand of denosumab. Prolia is also used to treat glucocorticoid-induced osteoporosis in men and women at high risk of bone fracture. Prolia is used to increase bone mass in men with osteoporosis with a high risk of bone fracture, and in women and men with a high risk of bone fracture caused by receiving treatments for certain types of cancer. The Prolia brand of denosumab is used to treat osteoporosis in postmenopausal women who have high risk of bone fracture. This may help to protect healthy cells from damage. Monoclonal antibodies are made to target and destroy only certain cells in the body. Prolia (denosumab) is a monoclonal antibody. US Residency: Must reside and receive treatment in USĭiagnosis: FDA Approved Diagnosis - See Program Website for Details What is Prolia Insurance: *See Additional Information section below ![]()
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